Defibrination syndrome in phlegmasia ceruleaolens.

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Defibrination syndrome in phlegmasia ceruleaolens.

MASSON, P. (1914) La Glande Endocrine de l'Intestin Chez l'Homme. C R. Acad. Sci. Paris, 158, 59. NICOLAS, A. (1891) Recherches sur l'Epithelium de l'Intestin Grele. Int. Mschr. Anat. Physiol. 8, 1. NISSEN, E.D. (1959) Consideration of the malignant carcinoid syndrome: primary argentaffinomas arising in benign cystic teratomas of the ovary. Obstet. Gynec. Surv. 14, 459. NOVAK, E. & NOVAK, E.R. ...

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Disseminated intravascular coagulation occurred in dogs given scorpion venom subcutaneously in doses of 3 mg./kg. body weight. Treatment with heparin reversed the coagulation abnormality of the syndrome and 10 out of 12 dogs survived. Necropsy findings in human patients stung by scorpions suggest that this syndrome also occurs in man.

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The defibrination syndrome arising during mitral valvotomy.

Edge and Bottrill (1959), in their recent analysis of 170 patients submitted to pulmonary resection, mention one death from uncontrollable haemorrhage, in which there was evidence of a clotting defect. The development of acute and sometimes fatal coagulation deficiencies during chest operations is well documented in the French and American literature (Mathey, Daumet, Soulier, Le Bolloch, and Fa...

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Pathogenesis of Fibrinolysis in Defibrination Syndrome: Effect of Heparin Administration.

CUTE HYPOFIBRINOGENEMIA may result from systemic intravascular coagulation ( defibrination ),or from spontaneous pathologic fibninolysis, or both. The pathogenesis of these conditions has been ascribed to the local release of thromboplastic substances,1’2 or fibrinolytic substances34 or a cornbination of these.5’6’7 Since either thromboplastic or fibrinolytic substances may reduce the level of ...

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Defibrination syndrome with defective thrombinfibrinogen reaction reversible by protamine.

A patient with the obstetric defibrination syndrome successfully treated with human fibrinogen is described. The blood not only contained low levels of fibrinogen capable of clotting but also contained an inhibitor of the thrombin-fibrinogen reaction. This was neutralized in vitro with protamine but it was not heparin. Neither abnormality was detected by a latex agglutination test for plasma fi...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1969

ISSN: 0032-5473

DOI: 10.1136/pgmj.45.519.48